Simulation of human vision by image evolution in light-excitable nonlinear optical mediums

The nonlinear optical membrane used for image processing was prepared using tetraethyl silicate by sol-gel method under mild conditions. Ru(bpy)3Cl2 (bpy, bipyridine) was immobilized in the sol-gel matrix. This light-excitable membrane containing Ru(bpy)3Cl2 as photocatalyst could catalyze the Belousov-Zhabotinsky reaction by illumination. Our results indicated that a fine-definition image processing could be autoperformed when projecting a picture on this medium. The imaging process was an image evolution process, which was similar to that of the human vision process.     

环境和生物样品中铂族金属的分析研究进展

评述了近年来环境和生物样品中痕量铂族金属的分析研究进展，重点介绍了样品的预处理和分离富集技术以及检测手段等。     

Sr2YRuO6有序双钙钛矿结构及其Mott绝缘体的研究

运用第一性原理方法对双钙钛矿Sr2YRuO6各种可能的无序结构和有序结构的能量进行计算,计算结果显示有序结构双钙钛矿具有最低能量,说明该结构最稳定,这一结果也与实验中样品的多晶样品X射线衍射图(XRD)中出现超晶格有序峰相符合。通过计算给出该材料的能带,显示该材料是Mott绝缘体,这一结论也与实验结果相一致。     

钙黄绿素蓝荧光法测定食品中的微量锌（Ⅱ）

本文研究了在ＣＴＭＡＢ存在下，用钙黄绿素蓝荧光法测定食品中的微量锌（Ⅱ）的实验条件。在本实验条件下，Ｚｎ（Ⅱ）与钙黄绿素蓝生成１：１的配合物使钙黄绿素蓝的荧光增强，最大激发波长和最大发射波长分别为３５３ｎｍ和４４０ｎｍ。     

重氮化5-氨基-吡唑还原合成5-H-吡唑衍生物

5-氨基吡唑类化合物,经重氮化后,在铜粉存在下,可高收率地生成相应的5-H-吡唑衍生物。研究证明,铜粉作为还原剂直接参与了反应。为考察反应的适用范围,选用含不同取代基的5氨基吡唑衍生物进行研究,结果表明,它们均能被还原,高收率地生成相应的还原产物。该方法操作简便、反应条件温和、时间短、产物易分离纯化。     

液相色谱专家系统中柱系统推荐规则的建立和验证

把分子结构和分子、离子静电作用力作为影响溶质保留值和选择性的基本点,提出了液相色谱专家系统柱系统推荐的基本规则,由此可以从溶质所包含的基团或官能团的信息进行色谱柱系统推荐。为了验证这些规则的正确性,应用几类常用的或典型的样品从分子结构通道进行液相色谱柱系统推荐,获得满意的结果。     

Synthesis,characterization, and theoretical studies of group 4 amido hydrotris(pyrazolyl)borate complexes

Titanium and zirconium amido complexes containing a hydrotris(pyrazolyl)borate (Tp) or hydrotris(3,5-dimethylpyrazolyl)borate (Tp*) ligand TpM(NMe(2))(3) (M = Ti, 1; M = Zr, 2) and Tp*M(NMe(2))(3) (M = Ti, 3; M = Zr, 4) were prepared by the reactions of M(NMe(2))(3)Cl (M = Ti, Zr) with sodium hydridotris(pyrazol-1-yl)borate and potassium hydridotris(3,5-dimethylpyrazol-1-yl)borate, respectively. The structures of 1, 2, and 4.CH(2)Cl(2) were determined by X-ray diffraction and show octahedral coordination geometry around the metal centers. Density functional theory calculations at the B3PW91 level were performed to understand the orientations and the rotational behavior of amido ligands in these metal complexes.     

Multifunctional peptide-assembled micelles for simultaneously reducing amyloid-β and reactive oxygen species

The excessive production and deposition of amyloid-β (Aβ) is one of the most important etiologies of Alzheimer''s disease (AD). The interaction between Aβ and metal ions produces aberrant reactive oxygen species (ROS), which induce oxidative stress and accelerate the progression of AD. To reduce Aβ plaques and ROS to maintain their homeostasis is an emerging and ingenious strategy for effective treatment of AD. Herein, we report the rational design of multifunctional micelles (MPGLT) based on a polymer-grafted peptide to simultaneously clear Aβ and ROS for AD therapy. The MPGLT integrating three functional peptides as a ROS scavenger (tk-GSH), β-sheet breaker (LP) and an autophagy activator (TK) respectively, could capture and degrade Aβ. Meanwhile, the tk-GSH on the surface of MPGLT effectively scavenges the intracellular ROS. Consequently, MPGLT reduced the cytotoxicity of Aβ and ROS. In vivo animal studies using an AD mouse model further showed that MPGLT could transport across the blood–brain barrier for decreasing the Aβ plaque and eliminating ROS in vivo. This peptide micelle-based synergistic strategy may provide novel insight for AD therapy.

Multifunctional micelles based on a peptide–polymer for simultaneously targeting Aβ degradation and ROS scavenging for AD therapy.     

Triangular halogen trimers. A DFT study of the structure, cooperativity, and vibrational properties

Triangular halogen trimers (RX)3, where X = Br, I and R represents H, H3C, H2FC, HF2C, F3C, CH2=CH, CH[triple bond]C, and Ph, have been investigated using the density functional theory in the Perdew, Burke, and Ernzerhof method. We report herein the optimized geometries of the stable structures, their vibrational frequencies, and binding energies with the two- and three-body terms. All trimer structures possess a cyclic array of halogen atoms in the type II approach by virtue of the nonspherical atomic charge distribution around the halogens. The Br...Br interactions in trimers are very weak, whereas the I...I interactions in trimers are relatively stronger. While all bromine trimers and most of iodine trimers are predicted to be noncooperative, three of iodine trimers show weak cooperativity. The analysis of vibration modes reveals that all halogen trimers exhibit no especially remarkable frequency shifts. It is also shown that the electrostatic contribution plays a major role in the halogen...halogen interactions in halogen trimers. In contrast to bromine trimers, the relative contribution of charge-transfer component to the halogen...halogen interactions becomes more important for iodine trimers.